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Death receptor-mediated exogenous pathways In the exogenous apoptotic pathways, cisplatin binds to death receptors such as tumor necrosis factor receptor 1 (TNFR1), TNFR2, and FAS on the cell membrane to activate caspase-8, which further activates caspase-3, ultimately leading to apoptosis [40]

Support for Addiction Recovery : NAD+ is used in addiction treatment programs due to its ability to repair brain function and reduce cravings, particularly in individuals recovering from substance abuse